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Thursday, April 16, 2026

Injectables & Adherence...

 

Since the beginning of HIV treatment, the game has been the same.  Medications have to be accessible, tolerable & reliable.  Then there's adherence.  The best meds in the world won't matter if they aren't taken regularly. 

90 - 95% adherence is what's needed for HIV meds to be effective & help prevent resistance.  The aim was to create regimens that were accessible with ease of regimen maintenance.  We went from handfuls of pills to a few, to a single pill.  Now there are injectable options given weekly, monthly, quarterly & at larger intervals.  Until a cure is found, they'll probably aim for annual injections.

For many adherence is a serious challenge.  Injectables could be a much better option for many.  After taking handfuls of pills daily, a single dose at wide intervals would be astounding.  Even if it was a weekly pill, that would be a drastic improvement.  

Adherence makes this all work.  Any threat to that is a threat to that person.

Cya...

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