Problematic Pieces...

 

The article I found this morning is a bit troublesome.  The title is, "Gene Therapy Can Effectively Eliminate HIV Infection."   The article covers the same info I did for a recent post.  It discussed deactivating the CCR5 mutation & snipping the virus from the cell.  The concept CRISPR has been around a bit.  The method has been studied for a while, still it isn't a proven strategy.  Thus far, it's been used in humanized mice.

Even though the title infers there's a cure for HIV via gene therapy, there isn't at this time.   Maybe this can be made to work in mice 100% of the time.  That doesn't mean it will automatically translate to any other animals or humans. 

Still the title remains & many people will read that & think they can be cured tomorrow.  Articles like this can do far more harm than they will inform of future possibilities.  Before you write, know your audience.  Albeit there was some serious jargon in this article, it was written to lean towards lay people, not medical professionals.  Even though the title is technically accurate, it's click bait & a false promise.  This type of writing is misleading, harmful & quite frankly disgusting.

Cya...

Bright Saturday...

 

The 1st week of May is almost over & the starting Saturday has decided to be bright.  It was nice to wake up to some sunny skies.  There's a bit of overcast, but we still have a lot of rain chances in the forecast.  The seas of yellow hell flowers are in bloom in the fields just outside town.  They're very pretty, but they try to kill me.  So, I'd rather the wind blow elsewhere. 

That's all for now.  House bills & errands have been handled for a bit.  Take care.

Cya...

Grey May...

 

It's a grey 5th of May.  So much for a bright new month.  It look's like a lot of the 1st half of this month will be gloomy, great more drear.   At least it's a little warmer.  I'm really over the 22/23 season of darkness & drear.  

That's it for now.  There's shopping & errand on the list for today.  Take care.

Cya...

Not Quite...

 

It looks like May is going to start off stormy.  As long as it's warmer I'll be happier.  I'm really tired of being cold.  Still, I'd rather it be bright.  

There's nothing gone on today.  We'll finish the house bills tomorrow.  Then most of May will be settled for those matters. 

That's all for now, take care.

Cya...

May Monthly Stuff...

 

It'll be a bit of busy day for us.  I need to get through my morning stuff & get cleaned up.   Then I'll need to eat & get trash to the curb.  It's also time to handle the 1st of the month stuff, errands & bills.  There weren't any new articles so that's not on the table today.  It's bright & warming up.   This could be the end of the 40s.  If so, I could finish up some winter cleaning soon.  I'll give it a bit to make sure it doesn't flip back again.  I've already started trying to wash things over a month ago.  Maybe this time it'll take.

Cya...

Another CRISPR ...

 

This article is a bit wordy, but worth it.  It's about reasearch using a dual CRISPR approach to cure humanized mice of HIV.   Some points;  this is research, CRISPR is gene editing, humanized mice carry human genes, cells or tissues.  

While on a long acting HIV medication, this dual approach would directly attack & remove HIV from infected cells.  Then it would inactivate the CCR5 mutations in these cells.  This similar to what happens to humans who have been cured via transplant.

This is still in the research phase & these are mice, even if humanized.  Even if this does work, they will have to ensure to impact every aspect in the body.  If not, the dormant HIV would eventually return.

This may sound like the rantings of a mad scientist in a horror movie, but the science is grounded.  Despite the mixed species aprroach, this may lead to a possible cure not involving some one getting a bone marrow transplant to treat leukemia. 

Something to keep an eye on.  Take cae.

Cya...

Hello May...

 

Well May finally got here.  I hope it brought some warmer temps & sunshine with it.  It's bright this morning, but still chilly.  We have to go shopping in a bit & this week will be 1st of month bills stuff.  There aren't any out of the ordinary appointments.  I'm getting a handle on the yard stuff.  It'll probably be done within a week or so.  Then on to the mass of blankets I need to wash & stow. 

That's it's for now.  Maybe Spring actually showed up.  Take care.

Cya...