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Tuesday, May 2, 2023

Another CRISPR ...

 

This article is a bit wordy, but worth it.  It's about reasearch using a dual CRISPR approach to cure humanized mice of HIV.   Some points;  this is research, CRISPR is gene editing, humanized mice carry human genes, cells or tissues.  

While on a long acting HIV medication, this dual approach would directly attack & remove HIV from infected cells.  Then it would inactivate the CCR5 mutations in these cells.  This similar to what happens to humans who have been cured via transplant.

This is still in the research phase & these are mice, even if humanized.  Even if this does work, they will have to ensure to impact every aspect in the body.  If not, the dormant HIV would eventually return.

This may sound like the rantings of a mad scientist in a horror movie, but the science is grounded.  Despite the mixed species aprroach, this may lead to a possible cure not involving some one getting a bone marrow transplant to treat leukemia. 

Something to keep an eye on.  Take cae.

Cya...

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